Move-in ready office spaces in Buffalo Seneca One

Fully furnished offices and team suites for 1–100 people — flexible terms, fully serviced, and IT-secure from day one.

  • Radio-Waves

    Fast, reliable Wi-Fi and on-site hospitality staff

  • Cash In Hand

    All amenities included — no hidden fees

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    Tour today, move in within days

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Buffalo Seneca One Private Office & Coworking Space, Open Coworking space with potted plants on the floor and large window views of downtown.
Buffalo Seneca One Private Office & Coworking Space, Private one person office with views of the water.
A modern office desk and chair in Serendipity Labs coworking space face a large window overlooking water, a distant shoreline, and cloudy sky. A potted plant and office supplies sit on the desk.
Modern office space with several black desks and chairs near large windows, offering a city view. Neutral-toned carpet, bright lighting, and a clean, minimalistic design—perfect for serendipity labs coworking or private offices and meeting rooms.
Buffalo Seneca One Private Office & Coworking Space, Private Team Room with views to outside.
Buffalo Seneca One Private Office & Coworking Space, Private Team Room with views to outside.
Buffalo Seneca One Office Space, Coworking Space, Meeting Rooms.
Buffalo Seneca One Private Office & Coworking Space, cafe area local brewed coffee.

Coworking & Office Space in Buffalo Seneca One

4.9 (66 Reviews)

1 Seneca Street
Buffalo, New York 14203
21st Floor

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Office Solutions | Why Work From Here | Virtual Tour

716-442-8843

Available 24/7

Industry leading member satisfaction

Serendipity Labs is Buffalo's best coworking option with the brand boasting a world-class average NPS Score of 83 from our members.

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What do you love about working at Serendipity Labs?

Amy G.

Buffalo - Seneca One

If you're looking for a workspace that actually energizes you, look no further than Serendipity Labs in Buffalo. From the moment you walk in, you're welcomed by an incredible team that makes you feel like more than just a member—they make you feel like part of the community. The amenities are top-tier (seriously—everything you need, nothing you don’t), and the events bring together smart, creative people who genuinely want to connect and collaborate. The open spaces strike the perfect balance between focus and interaction, making it easy to get work done or strike up a meaningful conversation. And let’s not forget the views—a daily reminder that you’re working in one of Buffalo’s most inspiring spaces. Whether you're a solo founder, remote employee, or growing team, Serendipity Labs Buffalo is the kind of place that makes you want to go to work. Highly recommend.
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Akbar G.

Buffalo - Seneca One

I stumbled across Serendipity Labs while visiting Buffalo. It’s an outstanding place to co-work. Excellent facility, very conducive work environment, excellent WiFi, wonderful hosts (David, Emily and team), and very reasonable rates. Highly recommend to all professionals who would benefit from their excellent co-working & shared office services.

Josue J.

Buffalo - Seneca One

The Serendipity Labs space is great for any type of meeting or offsite event. Spacious layout, inviting atmosphere and great views. Plus, David and Emily are fantastic; they truly support you throughout the whole process. We'll be back!

Sarah B.

Buffalo - Seneca One

Excellent management by the Serendipity team and a fabulous location to work from. I will definitely be turning to Serendipity for all upcoming coworking space needs.

Our workspace solutions in Buffalo Seneca One

Buffalo’s Seneca One Tower has become a prime central hub for the region’s growing startup and tech ecosystem for creative professionals, entrepreneurs and freelancers. At Serendipity Labs Buffalo Seneca One, professionals can choose from coworking memberships, private offices, and dedicated desks all within flexible workspaces that offer unique amenities in downtown Buffalo’s central business district. Serendipity Labs contributes to the growth of downtown Buffalo’s flexible workspace dynamic as part of the city’s continued development and expansion programs, giving local professionals a place to network and grow.

50% OFF FIRST MONTH
T&Cs Apply
A modern office desk and chair in Serendipity Labs coworking space face a large window overlooking water, a distant shoreline, and cloudy sky. A potted plant and office supplies sit on the desk.

Private Office Space

  • Private Offices with Flexible Terms
  • Team Suites and Hybrid Options
  • Fully Furnished, No Hidden Fees
From $799 / desk / month

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Meeting Rooms

  • Small Meeting Rooms for In-Person or Hybrid Collaboration, Interviews or Planning
  • Large Meeting Venue Ideal for Training, Events and Conferences
  • High-Speed WiFi and AV Technology Included
From $49 / hour

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50% OFF FIRST MONTH
T&Cs Apply

Coworking Space

  • Drop in When You Need a Place to Work
  • Daily Work Lounge and Private Day Offices Available
  • 10 Day and Monthly Membership Plans
From $25 / person / day

More About Coworking & Day Offices

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Buffalo Seneca One Private Office & Coworking Space, View of open Coworking area next to the Serendipity Labs logo.

Virtual Office Plans

  • Recognized Business Address and Mail Handling
  • Up to 16 Hours Monthly Drop-In Visits Included
  • Preferred Rates for Meeting Room Bookings
From $79 / month

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Set up your office in 3 simple steps

Book

Book

Tell us what you’re looking for and book a quick tour at your local Serendipity Labs.

Choose

Choose

Explore private offices, team suites, or shared plans — all fully furnished, IT-secure, and supported by on-site staff.

Work

Work

Start working right away with 24/7 access, all premium amenities included, and zero setup required.

Who we serve

Small businesses

Small businesses

Get a polished office presence with the flexibility you need, and without the cost or commitment of a traditional lease and on-site support from our team of hospitality pros.

Private Offices Coworking Small Meetings Virtual Address
Hybrid organizations

Hybrid organizations

Private office space designed be shared by hybrid teams without missing a beat — fully furnished, secure in-place technology, and scalable as requirements change.

Shared Office Space Collaboration Space Coworking & Drop-In Space
Corporate teams

Corporate teams

Serendipity Labs offers premium spaces, hybrid-ready services, and scalable plans for enterprise teams and their partners.

Custom Team Suites Training & Events Hybrid Teams Enterprise Coworking Memberships
Technology-driven businesses

Technology-driven businesses

Our enterprise-grade IT infrastructure delivers robust performance and reliability for digital first businesses with secure internet connectivity and uncontested bandwidth to our members.

Dedicated Office Space Compliant Team Suites Private Meeting Rooms Secure Coworking

Getting here

Map

Parking

  • Easily accessible from NYS I-190 and Buffalo Skyway (Rt 5)
  • Parking Option 1:  Street parking is available for $2 per hour, which you can pay for at the kiosks on the street with coins/credit card or with the Buffalo Roam App. 
  • Parking Option 2: The Seneca One Ramp can be accessed at 50 Exchange Street. There is a bridge connecting the ramp to Seneca One on level 3. On the street level, walking from the garage you would turn right on Washington towards Sahlen Field and then left into the Seneca One courtyard which leads to the East Entrance.
  • Parking Option 3: An open lot at the corner of Seneca Street and Pearl Street, which can be accessed on Pearl Street. Payment must be made at the kiosk in the center of the lot. Directly across Pearl street from the lot is the Seneca One courtyard which leads to the West Entrance.  Rates: 
    • $5.50 Daily Rate 
    • $3.00 evenings after 3:00pm 
    • $55.00 monthly parking (approximately) 

Transportation

  • NFTA Rail Seneca stop directly in front of the building
  • NFTA Bus Washington Station stop. Line within 1/4 mile (lines run every 10-20 min. weekdays):
    1, 2, 3, 4, 5, 6, 7, 8, 11, 14, 15, 16, 20, 24, 25, 40, 42, 60, 61, 64, 66, 67, 68, 69, 70, 72, 74, 75, 76, 79 81, 101, 106
  • Amtrak Station on Exchange St., right behind Seneca One
  • Reddy Bikeshare on site at Seneca One
Get Directions

Why you'll love working from here

Buffalo Seneca One Office Space, Coworking Space, Meeting Rooms.

Benefit from the agility of a shared workspace in Seneca One – Buffalo’s most sought-after address, recently renovated and featuring panoramic views in a safe and secure environment.

Private & Team Offices
Private & Team Offices
Meetings & Events
Meetings & Events
Coworking & Drop-In
Coworking & Drop-In
Local hosts

Meet your local hosts

From day one our Buffalo coworking space’s onsite team, led by Marla, make getting work done seamless. Whether it is booking meeting rooms, handling mail, providing excellent IT support or giving tours of the space, they keep your day running smoothly. Additionally, our onsite team regularly facilitates professional introductions and invites teams to community events such as happy hours, lunch & learns, networking meetups, and other social gatherings. By connecting you to resources and other members our team helps you stay productive and take full advantage of everything the workspace has to offer.

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Welcome to an office with real perks, inside and out

Located in one of Buffalo Seneca One's most vibrant business hubs, our space offers more than four walls — it offers convenience, connection, and a community that feels like your own.

  • Sweeping views of Buffalo, Lake Erie, Canada and Niagara Falls

  • Onsite fitness center and cross-fit gym

  • Fully renovated lobby featuring a full bar, food hall and and Other Half taproom

  • Beautifully landscaped courtyard with ample seating areas

  • Onsite parking garage with direct access to lobby

  • Located directly next to the Metro Rail Seneca Station

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What makes Buffalo Seneca One stand out

Serendipity Labs Buffalo occupies Buffalo’s tallest building, the Seneca One Tower. The prime location in the heart of the central business district offers Lab members lots of local retail, wellness, and hospitality options. The closest are Southern Tier Brewing Company, a local favorite brewery just steps from the building, and Fountain Plaza, with an onsite CrossFit gym and easy access to dining, transit, and entertainment throughout downtown.

Catch a game at nearby Sahlen Field or KeyBank Center

Unwind at a concert at Canalside or try your luck at Seneca Buffalo Creek Casino

Steps from Buffalo City Hall, the Convention Center, various hotels and eateries

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Everything you need, already included

Our Seneca One Buffalo offices come equipped with premium amenities — no upgrade fees, access passes, or surprise add-ons. Unlike other workspaces, we don't charge extra for the basics — it's all included from the start, just like it should be.

Start working right away with fully furnished offices

Step into a focus room for calls, recharge in a retreat or stretch out in beautifully designed common areas.

Protect your data and workflows with secure, compliance-ready IT

Built for HIPAA, SOX, DoD, and FINRA standards, our private network keeps your business protected — no DIY IT required.

Make every visit feel professional with hospitality-led support

Our on-site team handles reception, mail, and daily service so you can focus on your work — and make the right impression.

Stay productive all day with private rooms and shared lounges

Book a private meeting space, step into a focus room, or recharge in beautifully designed common areas.

Fuel your day with complimentary drinks

Enjoy unlimited coffee, tea, and fruit-infused water — always fresh, always free, no kitchen stocking required.

Make valuable connections with local events and meetups

From professional development to casual socials, our local teams host optional events that help you connect, learn, and thrive.

Why choose Serendipity Labs

Other Providers
Hidden fees for basics like coffee, set-up, and move-out
Transparent pricing with no surprise fees
Unreliable, unsecure WiFi
Fast, secure internet for your team
Loud, chaotic coworking spaces that don’t reflect your brand
A professional, quiet environment designed for work
Limited meeting rooms and cramped phone booths
A variety of fully equipped meeting rooms so your team has space to focus and collaborate
Shared staff and “big box” operations with little focus on you
Dedicated on-site teams not just trained in hospitality, it’s in their DNA

More than office space — a workplace that works for you

Professional. Thoughtfully designed. Backed by real hospitality.

Built for work

Designed to inspire — so you can stay focused and productive.

Hospitality-driven support

Our team handles the details — so you can focus on the work that matters.

Transparent pricing

Coffee, Wi-Fi — it’s all included. No surprise fees. No fine print.

Designed for serendipity

From lounges to meeting spaces, our environments are made to spark connection and new ideas.

Ready to take a closer look at Serendipity Labs?

Find out if our flexible office solutions are a fit for you with a quick tour.

  • Tour available spaces with local hosts Tour available spaces with local hosts
  • Get clear pricing up front — no hidden fees, no fine print Get clear pricing up front — no hidden fees, no fine print
  • No pressure, just helpful info No pressure, just helpful info
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Frequently Asked Questions

Lab memberships can include 1 person, 2 person and 4-person private offices. Additionally, larger configurations can be quoted to your unique specifications. Coworking plans include dedicated desks, monthly all access memberships, and virtual office solutions. Each plan provides access to open workspace areas, meeting rooms, and other premium amenities designed for productivity and flexibility.
Our Buffalo Seneca One location caters to all industries with a focus on professionals from technology, finance, creative professionals, and freelancers that make up Buffalo's growing startup ecosystem. Located in the famous Seneca One Tower, Serendipity Labs offers members a prime address in Buffalo, which is critical in the expanding tech and finance sectors.
The companies based in Seneca One Tower represent Buffalo’s growing technology, finance, and creative sectors. The building is home to M&T Bank’s innovation hub, the 43North startup accelerator, and professional-services firms supporting the region’s fintech and construction communities. Serendipity Labs complements these industries with private offices for financial and legal teams, coworking memberships for entrepreneurs and designers, and virtual offices for remote firms expanding into Western New York’s professional market.

There is nothing better than seeing it for yourself.

 Spend 30 minutes with us to learn more about how we can help you.​​

Prefer to Call Us? 866-907-7832

We can be reached between 8am-6pm EST, or to chat live during business hours.

There is nothing better than seeing it for yourself.

 Spend 30 minutes with us to learn more about how we can help you.​​

Prefer to Call Us? 866-907-7832

We can be reached between 8am-6pm EST, or to chat live during business hours.